THE ROLE OF ALKALINE PHOSPHATASE IN THE DEVELOPMENT OF ENDOCRINE DISEASES
Abstract
Endocrine diseases encompass a wide range of disorders affecting hormone-producing glands, leading to dysregulation of various physiological processes. Alkaline phosphatase (ALP), an enzyme implicated in numerous cellular functions, has emerged as a potential player in the pathogenesis of endocrine disorders. This article reviews the current understanding of the role of ALP in the development of endocrine diseases, exploring its involvement in various endocrine organs and the mechanisms underlying its contribution to disease pathogenesis. Insights into the interplay between ALP and endocrine disorders may pave the way for novel diagnostic and therapeutic strategies for managing these conditions.
Keywords
Alkaline phosphatase, Endocrine diseases, Thyroid disorders
References
Whyte, Michael P. "Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization." Endocrine reviews 15.4 (1994): 439-461.
Gutman, Alexander B. "Serum alkaline phosphatase activity in diseases of the skeletal and hepatobiliary systems: A consideration of the current status." The American Journal of Medicine 27.6 (1959): 875-901.
Fernandez, Nicole J., and Beverly A. Kidney. "Alkaline phosphatase: beyond the liver." Veterinary clinical pathology 36.3 (2007): 223-233.
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Copyright (c) 2024 Mamatkulov Doniyor Anvarovich, Yuldosheva Manzura Mirzaevna
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