This study investigates the potential anti-hyperglycemic effect of Glipizide implants in Alloxan-induced diabetic rabbits. Glipizide, a widely used oral hypoglycemic agent, has been formulated into sustained-release implants to provide continuous therapeutic levels. The study utilized a rabbit model of diabetes induced by Alloxan administration and examined the glucose-lowering effects of Glipizide implants over a specified period. The results revealed a significant reduction in blood glucose levels following the implantation of Glipizide, demonstrating its potential as a novel therapeutic approach for managing hyperglycemia in diabetic rabbits. This research sheds light on the effectiveness of implantable Glipizide for diabetes management and opens avenues for further investigation into implant-based treatments for diabetes

Glipizide implants, Alloxan-induced diabetes, sustained-release

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